Clever, inquisitive rats and sweet, quiet mice make fantastic pets. When your rat or mouse forms a bond with you and starts hanging out on your shoulder or in your pocket, it can be a great feeling. On the other hand, if you decide to parent rats or mice, prepare to be “marked” in a way that doesn’t exactly smell fresh!
It’s common for rats and mice to mark their territory and “advertise” themselves to potential mates. If that territory is you, you’ll see small droplets or even larger patches of urine on your clothes. So, once the deed is done, how do you rescue your clothes from forever smelling like rodent pee? Check out these ideas.
Note: Wear gloves and a mask when dealing with rodent urine on clothes, especially if you’re dealing with a rat or mouse infestation in your home. Some diseases can be transmitted to humans, so it’s best to be safe.
The 4 Tips on How to Remove Rat and Mouse Stains from Clothes
1. Wash Clothes at a Hot Temperature
Washing the affected clothes in a washing machine at a high temperature is a great way to get rid of bacteria and germs. This disinfects them and is more likely to eliminate the awful yellow stains than a cold water wash. With any luck, your detergent and softener will take care of the rest.
Sometimes, there are reasons why you can’t wash some clothes in hot water. You may be worried about colors running, clothes shrinking, or other damage you’d rather avoid.
If that is the situation you’re in, and there’s only a tiny amount of urine on your clothes, a cooler wash may do the trick. If you’re dealing with tough stains that a regular wash isn’t fixing, check out one of the other tips below.
2. Soak Clothes in Baking Soda

Baking soda has many uses, including removing tough stains due to its abrasive texture. It’s also a powerful deodorizer, so try mixing baking soda with warm water in a sink or bathtub, depending on how big your pile of clothes is.
Stir the mixture to ensure the baking soda can work to its maximum potential, then let the clothes soak for 15 to 20 minutes. When the time is up, rinse the clothes thoroughly and wash them normally in your machine.
3. Soak Clothes in Enzyme Detergent
An alternative to using baking soda is to soak your clothes in the same way but in an enzyme detergent instead. Enzymes naturally break down tough stains, and it could be worth trying if your other methods aren’t cutting it. Use hot water if it’s suitable for the fabric you’re washing. When you’ve finished soaking, wash your clothes as usual.
You can find enzyme cleaners specifically for pet stains and smells in some supermarkets, hardware stores, and pet stores. Follow the instructions on the bottle, as they may vary by product.
If you're trying to find an enzyme cleaner that does it all, we highly recommend our favorite cleaner, the Hepper Advanced Bio-Enzyme Pet Stain & Odor Eliminator Spray.
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4. Use White Vinegar

Like baking soda, distilled white vinegar is a simple yet powerful cleaning product. It may surprise some to learn that, despite white vinegar’s strong acidic smell, it’s also great for eliminating bad smells.
Mix two parts of water (hot or cold, depending on your fabric type) with one part of vinegar in a sink, bucket, or washtub. Let the clothes soak for around 45 minutes. If the stain isn’t completely gone when the 45 minutes are up, let them soak for longer. Finally, wash the clothes as usual in your machine.
FAQ
Can Rat Urine be Washed Out of Clothes?
Yes, you can try a few methods, including regular laundry washing and using products like white vinegar and baking soda. With particularly tough stains, you may need to repeat the method you’ve chosen a couple of times.
Can Pet Rat and Mouse Urine Carry Diseases?
Rats are absolutely lovely pets, but it’s still possible for pet rats and mice to spread certain diseases to humans, though the chance of this happening is lower than with wild rats. If you keep your pet rat or mouse’s living environment as clean as possible, the possibility of your pet rats spreading diseases to you via urine or feces will be reduced.

Can Breathing Rat or Mouse Urine Make You Sick?
Though rare, Hantavirus Pulmonary Syndrome can be caused by inhaling particles from rodent droppings, most commonly from mouse droppings.
Why Do My Pet Rats Pee on Me?
Rats leave urine trails to mark their territory or to “broadcast” their sexual availability. It’s a form of communication in the rat world!
Can Pet Rats be Litter Trained?
Yes! Many rat parents put a rat-sized litter tray in the corner of the cage. Some use treats when the rat uses the box to encourage them to continue using it. Rats are intelligent and are certainly capable of learning to use a litter box, though it may take a bit longer with some. Mice can also be litter-trained, but it may be a little harder.

Conclusion
Though it’s impossible not to love our adorable rodent friends, we get how frustrating it can be to feel like a giant bathroom every time they interact with us! To improve the situation, consider using “rat or mouse clothes” that you wear every time you interact with your pet to avoid ending up with stained clothes. You can wash them using one of the methods described above.
It’s also key to keep your rat or mouse’s enclosure squeaky clean to encourage them to use the bathroom in there as much as possible. Rats are clean animals despite their reputation and will avoid smelly, soiled places for using the bathroom. You can also work on litter training; though it may take some time, it’s certainly worth the effort!
- https://denverwashandfold.com/blog/what-is-enzymatic-laundry-detergent
- https://www.howtocleanstuff.net/how-to-remove-urine-stains-from-clothing/
- https://resources.pangovet.com/pet-lifestyle/rodents/how-to-get-mouse-urine-smell-out-fabric/
- https://www.hunker.com/13422762/how-to-clean-mouse-urine-from-clothes
- https://tide.com/en-us/how-to-wash-clothes/how-to-do-laundry/remove-urine-smell-clothes
- https://www.health.ny.gov/diseases/communicable/hantavirus/fact_sheet.htm#:~:text=Hantavirus%20is%20spread%20from%20wild,such%20as%20sweeping%20or%20vacuuming.
- https://my.clevelandclinic.org/health/diseases/17897-hantavirus-pulmonary-syndrome-hps
- https://www.dhs.wisconsin.gov/disease/animal-safety.htm#:~:text=Many%20people%20own%20and%20enjoy,and%20spreading%20germs%20to%20humans.
- https://vethelpdirect.com/vetblog/2021/08/17/can-you-catch-any-diseases-from-pet-rats/
- https://animals.mom.com/train-rats-use-litter-box-10648.html
Featured Image Credit: Akifyeva S, Shutterstock
Contents
- The 4 Tips on How to Remove Rat and Mouse Stains from Clothes
- 1. Wash Clothes at a Hot Temperature
- 2. Soak Clothes in Baking Soda
- 3. Soak Clothes in Enzyme Detergent
- 4. Use White Vinegar
- FAQ
- Can Rat Urine be Washed Out of Clothes?
- Can Pet Rat and Mouse Urine Carry Diseases?
- Can Breathing Rat or Mouse Urine Make You Sick?
- Why Do My Pet Rats Pee on Me?
- Can Pet Rats be Litter Trained?
- Conclusion